SCHEMBL8716757

SCHEMBL8716757

CC(=O)OC(C)Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.56
SRR Q9GZT4 2/20 0.53
PSAT1 Q9Y617 2/20 0.53
PPARG P37231 8/20 0.51
PPARA Q07869 6/20 0.51
ACACB O00763 1/20 0.51
MME P08473 3/20 0.50
ACE P12821 3/20 0.50
CPA1 P15085 2/20 0.50
ACE2 Q9BYF1 2/20 0.50
PDCD1 Q15116 1/20 0.49
CD274 Q9NZQ7 1/20 0.49
FFAR1 O14842 1/20 0.49
ABCC4 O15439 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
TSHR P16473 1/20 0.47
PTGS1 P23219 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3505882 0.89 ALDH1A1 (0.52) SRRLMNATSHRPTGS1
SCHEMBL9028692 0.89 ALDH1A1 (0.52) SRRLMNATSHRPTGS1
SCHEMBL5617244 0.89 ALDH1A1 (0.52) SRRLMNATSHRPTGS1
SCHEMBL962571 0.89 TSHR (0.47) MMP12LMNATSHRPTGS1
SCHEMBL8155949 0.87 SMN1; SMN2 (0.50) MMP12PPARGPPARAACACBPDCD1
SCHEMBL8149286 0.85 HSD17B10 (0.54) MMP12PPARGPPARALMNAGAA
SCHEMBL114063 0.85 SRR (0.55) SRRPSAT1PPARGPPARAACACB
SCHEMBL22474253 0.83 SRR (0.50) SRRPSAT1PPARGPPARAACACB
Acetic Acid SCHEMBL9809891 0.83 SRR (0.53) SRRPSAT1PPARGPPARAACACB
SCHEMBL22474260 0.82 SRR (0.53) SRRPSAT1PPARGPPARAACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5741438-A Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as an effective component, and liquid crystal element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-21 US disclosed
EP-0395390-B1 Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same SUMITOMO CHEMICAL CO (JP) 1994-09-28 EP disclosed
EP-0395390-A1 Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-31 EP disclosed