Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28381254 | 0.90 | LMNA (0.51) | PTGS1GAAPOLBLMNAHSD17B10 | |
| SCHEMBL28382770 | 0.85 | LMNA (0.54) | PTGS1GAAPOLBLMNAHSD17B10 | |
| SCHEMBL8655098 | 0.84 | HPGD (0.47) | PTGS1GAALMNAHSD17B10HPGD | |
| SCHEMBL11305384 | 0.83 | LMNA (0.46) | PTGS1GAALMNAHSD17B10HPGD | |
| SCHEMBL8795201 | 0.81 | GAA (0.45) | PTGS1GAAPOLBLMNAHSD17B10 | |
| SCHEMBL28382127 | 0.78 | PTGS1 (0.55) | PTGS1GAAPOLBLMNAHSD17B10 | |
| SCHEMBL872880 | 0.76 | ALDH1A1 (0.41) | PTGS1GAAPOLBLMNAHSD17B10 | |
| SCHEMBL2347168 | 0.75 | ALDH1A1 (0.43) | PTGS1GAAPOLBLMNAHSD17B10 | |
| SCHEMBL11385199 | 0.75 | ALDH1A1 (0.43) | PTGS1GAAPOLBLMNAHSD17B10 | |
| SCHEMBL30678705 | 0.74 | ALPL (0.74) | PTGS1GAAPOLBLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028115-A | APPLYING BRANCHED POLY(METHYLETHER HYDROQUINONE SULFONATE) OR DERIVATIVE | RUSH-PRESBYTERIAN-ST. LUKE'S MEDICAL CENTER (US) | 2000-02-22 | — | — | US | claimed |