SCHEMBL81504

SCHEMBL81504

CC(C)c1ccc(C2=C(c3nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n3)O2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.35
NPC1 O15118 3/20 0.35
TP53 P04637 3/20 0.35
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HDAC6 Q9UBN7 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
NOTUM Q6P988 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PAX8 Q06710 1/20 0.32
NOD2 Q9HC29 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2403397 0.85 RAB9A (0.43) RAB9ANPC1TP53MAPTKDM4E
SCHEMBL14039148 0.83 RAB9A (0.42) RAB9ANPC1TP53MAPTKDM4E
SCHEMBL14589683 0.77 PTGS1 (0.40) RAB9ANPC1TP53MAPTKDM4E
SCHEMBL3312117 0.77 ADK (0.41) RAB9ANPC1TP53MAPTKDM4E
SCHEMBL1817406 0.76 S1PR1 (0.36) RAB9ANPC1TP53MAPTKDM4E
SCHEMBL3311314 0.70 HTT (0.36) RAB9ANPC1MAPTMEN1KMT2A
SCHEMBL14036432 0.69 TSHR (0.33) RAB9ANPC1NPSR1PAX8
SCHEMBL8412982 0.69 NPC1 (0.38) RAB9ANPC1MAPTKDM4EMEN1
SCHEMBL22129836 0.69 NPC1 (0.41) RAB9ANPC1MAPTKDM4EMEN1
SCHEMBL80269 0.69 NPC1 (0.41) RAB9ANPC1MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705007-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2012-06-06 EP disclosed
US-8127675-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20100047719-A1 IMAGE RECORDING METHOD INNO TOSHIFUMI 2010-02-25 US disclosed
US-20100005989-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION 2010-01-14 US disclosed
EP-1669194-B1 Lithographic printing plate precursor and method of producing printing plate FUJIFILM CORP (JP) 2008-05-28 EP disclosed
US-20080072779-A1 PROTECTING/PACKAGING MATERIAL FOR LITHOGRAPHIC PRINTING PLATE AND METHOD FOR PACKAGING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
EP-1588858-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2007-08-08 EP disclosed
US-20070144384-A1 Image recording method FUJI PHOTO FILM CO., LTD (JP) 2007-06-28 US disclosed
US-20060216642-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2006-09-28 US disclosed
EP-1705007-A2 Lithographic printing plate precursor and lithographic printing method Fuji Photo Film Co., Ltd. (JP) 2006-09-27 EP disclosed
EP-1669194-A1 Lithographic printing plate precursor and method of producing printing plate FUJI PHOTO FILM CO., LTD. (JP) 2006-06-14 EP disclosed
EP-1588858-A2 Lithographic printing plate precursor and lithographic printing method Fuji Photo Film Co., Ltd. (JP) 2005-10-26 EP disclosed