SCHEMBL1817406

SCHEMBL1817406

CCCc1ccc(C2=C(c3nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n3)O2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 4/20 0.36
S1PR4 O95977 1/20 0.36
S1PR3 Q99500 1/20 0.36
S1PR5 Q9H228 1/20 0.36
NISCH Q9Y2I1 1/20 0.34
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
MAPT P10636 2/20 0.33
GFER P55789 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 2/20 0.33
PDE10A Q9Y233 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
DGAT1 O75907 1/20 0.32
TP53 P04637 1/20 0.31
HTR1D P28221 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14040238 0.86 S1PR1 (0.39) S1PR1S1PR4S1PR3S1PR5NISCH
SCHEMBL2833718 0.77 RAB9A (0.47) S1PR1S1PR4S1PR5NISCHNPC1
SCHEMBL81504 0.76 RAB9A (0.35) NISCHNPC1RAB9AMAPTSMN1; SMN2
SCHEMBL2832962 0.73 TP53 (0.43) S1PR1S1PR5NISCHNPC1RAB9A
SCHEMBL3343534 0.71 TP53 (0.42) S1PR1S1PR5NISCHNPC1RAB9A
SCHEMBL3311317 0.70 L3MBTL1 (0.42) NPC1RAB9AMAPTALDH1A1NPSR1
SCHEMBL27100735 0.68 TP53 (0.39) NPC1RAB9AMAPTSMN1; SMN2ALDH1A1
SCHEMBL21887379 0.67 NISCH (0.47) S1PR1S1PR4S1PR3S1PR5NISCH
SCHEMBL8412982 0.67 NPC1 (0.38) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL22129836 0.67 NPC1 (0.41) NPC1RAB9AMAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7939240-B2 Lithographic printing plate precursor and method of producing printing plate FUJIFILM CORPORATION (JP) 2011-05-10 US disclosed
US-20060127810-A1 Lithographic printing plate precursor and method of producing printing plate FUJI PHOTO FILM CO. LTD. 2006-06-15 US disclosed
US-20050233251-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2005-10-20 US disclosed