Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487402 | 0.79 | EGFR (0.30) | EGFRCSNK2A1PIM1CSNK2A2CSNK2B | |
| SCHEMBL2998232 | 0.79 | EGFR (0.46) | EGFRAURKARPS6KB1CSNK2A1CSNK2A2 | |
| SCHEMBL8490286 | 0.75 | KMT2A (0.40) | EGFRAURKARPS6KB1GRM4CSNK2A1 | |
| SCHEMBL2986229 | 0.73 | AURKA (0.45) | EGFRAURKARPS6KB1CSNK2A1KDR | |
| SCHEMBL8082010 | 0.71 | SYK (0.46) | EGFRCSNK2A1KDRERBB2NPC1 | |
| SCHEMBL8096003 | 0.68 | KDM4C (0.38) | EGFRERBB2ALDH1A1 | |
| SCHEMBL8093494 | 0.68 | XDH (0.33) | KDRPOLBERBB2ALDH1A1NPC1 | |
| SCHEMBL8150759 | 0.68 | GRM1 (0.61) | EGFRERBB2 | |
| SCHEMBL4858939 | 0.67 | AURKA (0.57) | EGFRAURKARPS6KB1ERBB2 | |
| SCHEMBL4864883 | 0.67 | AURKA (0.57) | EGFRAURKARPS6KB1ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127374-A | AN ENZYME INHIBITOR FOR TREATING CANCER, RESTENOSIS, ATHEROSCLEROSIS, ENDOMETRIOSIS AND PSORIASIS | WARNER-LAMBERT COMPANY (US) | 2000-10-03 | — | — | US | disclosed |