Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150757 | 0.79 | PDE7A (0.38) | EGFRKDRPIM1CSNK2A2CSNK2B | |
| SCHEMBL2998232 | 0.78 | EGFR (0.46) | EGFRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL8490286 | 0.73 | KMT2A (0.40) | EGFRKDRPIM1CSNK2A2CSNK2B | |
| SCHEMBL2986229 | 0.70 | AURKA (0.45) | EGFRKDRCSNK2A1 | |
| SCHEMBL8082010 | 0.70 | SYK (0.46) | EGFRKDRCSNK2A1 | |
| SCHEMBL2989950 | 0.64 | EGFR (0.47) | EGFRKDRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2991831 | 0.64 | DYRK1A (0.47) | EGFRKDRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL2991658 | 0.64 | EGFR (0.47) | EGFRKDRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL8096003 | 0.63 | KDM4C (0.38) | EGFR | |
| SCHEMBL8093494 | 0.63 | XDH (0.33) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999006378-A1 | IRREVERSIBLE INHIBITORS OF TYROSINE KINASES | WARNER-LAMBERT COMPANY (US) | 1999-02-11 | — | — | WO | claimed |