Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 11/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154275 | 0.77 | ALDH1A1 (0.50) | TNKSTNKS2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8150334 | 0.75 | ALDH1A1 (0.50) | MAPTL3MBTL1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8148345 | 0.74 | ALDH1A1 (0.48) | TNKSTNKS2ALDH1A1KDM4ERAB9A | |
| SCHEMBL14133855 | 0.73 | MAPT (0.58) | TNKSTNKS2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL22045050 | 0.72 | TNKS (0.55) | TNKSTNKS2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8150807 | 0.71 | NPC1 (0.41) | TNKSTNKS2MAPTALDH1A1KDM4E | |
| SCHEMBL13066112 | 0.71 | GPR3 (0.43) | MAPTL3MBTL1ALDH1A1KDM4ERAB9A | |
| SCHEMBL16283914 | 0.71 | MAPT (0.56) | TNKSTNKS2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8537997 | 0.69 | L3MBTL1 (0.41) | TNKSTNKS2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL23139905 | 0.69 | MAPT (0.53) | TNKSTNKS2MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013807-A | Antitumor tetracyclic compounds | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5852204-A | Pyrrolo 3,2-b-!-carbazoles and 1H 1!benzothieno 2,3-f! indoles having anti-tumor activity | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1998-12-22 | — | — | US | disclosed |