Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812523 | 0.82 | P2RX1 (0.34) | P2RX1RAPGEF4GAARXRARXRB | |
| SCHEMBL456893 | 0.78 | P2RX1 (0.36) | P2RX1RAPGEF4GAARXRARXRB | |
| Benzene SCHEMBL30336225 | 0.75 | TSHR (0.43) | P2RX1RXRARXRBTSHRMAPK1 | |
| SCHEMBL41567 | 0.75 | CES2 (0.44) | RAPGEF4RXRARXRBTSHRMAPK1 | |
| SCHEMBL215855 | 0.74 | ALDH1A1 (0.41) | P2RX1GAATSHRTACR1 | |
| Toluene SCHEMBL6239727 | 0.74 | TSHR (0.41) | P2RX1RAPGEF4RXRARXRBNFE2L2 | |
| Toluene SCHEMBL6538388 | 0.74 | TSHR (0.41) | P2RX1RAPGEF4RXRARXRBNFE2L2 | |
| SCHEMBL30509222 | 0.73 | CES2 (0.39) | RAPGEF4RXRARXRBTSHRIKBKB | |
| SCHEMBL6866090 | 0.73 | CES2 (0.42) | RAPGEF4RXRARXRBTSHRMAPK1 | |
| SCHEMBL226082 | 0.73 | CES2 (0.42) | RAPGEF4RXRARXRBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058372-B2 | Catalyst composition II | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-11-15 | — | — | US | claimed |
| US-20080319147-A1 | Catalyst Composition II | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-12-25 | — | — | US | claimed |
| US-7371803-B2 | Catalyst composition II | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-05-13 | — | — | US | claimed |
| US-20070066776-A1 | Catalyst composition II | SOLAN GREGORY A | 2007-03-22 | — | — | US | claimed |
| US-7189791-B2 | Catalyst composition II | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-03-13 | — | — | US | claimed |
| US-20040266961-A1 | Catalyst composition II | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-30 | — | — | US | claimed |
| US-8058372-B2 | Catalyst composition II | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-7820582-B2 | Catalyst composition | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20080319147-A1 | Catalyst Composition II | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-12-25 | — | — | US | disclosed |
| US-7371803-B2 | Catalyst composition II | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-05-13 | — | — | US | disclosed |
| US-20070191607-A1 | Catalyst composition | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-08-16 | — | — | US | disclosed |
| US-7217675-B2 | Catalyst composition | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-20070066776-A1 | Catalyst composition II | SOLAN GREGORY A | 2007-03-22 | — | — | US | disclosed |
| US-7189791-B2 | Catalyst composition II | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-03-13 | — | — | US | disclosed |
| EP-1641842-A2 | POLYMERIZATION AND OLIGOMERIZATION CATALYST WITH TRIDENTATE OR TETRADENTATE LIGAND | Exxonmobil Chemical Patents Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| EP-1603956-A2 | CATALYST COMPOSITION | ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20040266961-A1 | Catalyst composition II | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-30 | — | — | US | disclosed |
| WO-2004106390-A2 | POLYMERIZATION AND OLIGOMERIZATION CATALYST WITH TRIDENTATE OR TETRADENTATE LIGAND | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242893-A1 | Catalyst composition | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |
| WO-2004085497-A2 | CATALYST COMPOSITION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242893-A1 | Catalyst composition | MLX, BMX, CDYL | P2RX1 208/4885RAPGEF4 4460/4885GAA 3731/4885 |
| US-20040266961-A1 | Catalyst composition II | MLX, CBX2, BMX | P2RX1 583/4885RAPGEF4 4437/4885GAA 3583/4885 |
| US-20070191607-A1 | Catalyst composition | MLX, LMNB2, TPX2 | P2RX1 873/4885RAPGEF4 3996/4885GAA 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.