Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | FPR1 | P21462 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28131042 | 0.86 | NFE2L2 (0.58) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL10651848 | 0.84 | TSHR (0.62) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14880488 | 0.84 | KCNJ1 (0.63) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL3793588 | 0.82 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL27102191 | 0.82 | MAOB (0.62) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL13265689 | 0.81 | ALDH1A1 (0.55) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14191204 | 0.80 | LTA4H (0.70) | MAPTALDH1A1TP53HTTLMNA | |
| SCHEMBL28218566 | 0.80 | LTA4H (0.51) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL2099512 | 0.80 | CHRM2 (0.66) | MAOBLTA4H | |
| SCHEMBL11685990 | 0.79 | ALDH1A1 (0.57) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090854-A | Aryloxyanilides and related compounds | BRISTOL-MEYERS COMPANY (US) | 2000-07-18 | — | — | US | disclosed |
| WO-1999048859-A1 | ARYLOXYANILIDES AND RELATED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-30 | — | — | WO | disclosed |