Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156645 | 0.93 | PTGS2 (0.43) | PTGS2AKR1C3APEX1KDM4EKMT2A | |
| SCHEMBL8151997 | 0.88 | APEX1 (0.38) | PTGS2APEX1POLBTDP1HTT | |
| SCHEMBL9340619 | 0.86 | CYP3A4 (0.46) | AKR1C3APEX1KDM4EKMT2AALDH1A1 | |
| SCHEMBL8152330 | 0.86 | CYP3A4 (0.46) | AKR1C3APEX1KDM4EKMT2AALDH1A1 | |
| SCHEMBL8143779 | 0.86 | MAPT (0.46) | PTGS2AKR1C3APEX1KMT2APOLB | |
| SCHEMBL8153430 | 0.85 | GRIK1 (0.46) | AKR1C3APEX1ALDH1A1POLBCYP2C9 | |
| SCHEMBL8380576 | 0.85 | GRIK1 (0.46) | AKR1C3APEX1ALDH1A1POLBCYP2C9 | |
| SCHEMBL8156850 | 0.84 | DPEP1 (0.39) | APEX1KDM4EALDH1A1POLBLMNA | |
| SCHEMBL8144233 | 0.84 | DPEP1 (0.41) | APEX1KMT2APOLBPKMMEN1 | |
| SCHEMBL8150918 | 0.83 | PDCD1 (0.51) | APEX1KDM4EPOLBFBP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |