Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143834 | 0.88 | APEX1 (0.36) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL8152330 | 0.86 | CYP3A4 (0.46) | MAPTAKR1C3KMT2AMEN1TDP1 | |
| SCHEMBL9340619 | 0.86 | CYP3A4 (0.46) | MAPTAKR1C3KMT2AMEN1TDP1 | |
| SCHEMBL8151236 | 0.86 | PTGS2 (0.44) | MAPTPTGS2AKR1C3KMT2AMEN1 | |
| SCHEMBL8157079 | 0.85 | MEN1 (0.46) | MAPTAKR1C2PTGS2AKR1C3KMT2A | |
| SCHEMBL8152924 | 0.84 | TRPA1 (0.38) | MAPTPTGS2KMT2AMEN1TDP1 | |
| SCHEMBL8150918 | 0.83 | PDCD1 (0.51) | MAPTFBP1TDP1POLBAPEX1 | |
| SCHEMBL8150606 | 0.82 | GLO1 (0.54) | MAPTKMT2AMEN1FBP1MAPK1 | |
| SCHEMBL8144233 | 0.81 | DPEP1 (0.41) | MAPTKMT2AMEN1TDP1POLB | |
| SCHEMBL8151214 | 0.81 | DPEP1 (0.41) | TDP1POLBAPEX1HTTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |