Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 11/20 | 0.74 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.74 |
| ▸ | TGM2 | P21980 | 2/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.60 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.60 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RAF1 | P04049 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539172 | 0.90 | MTNR1B (0.61) | MTNR1BMTNR1ATGM2ALDH1A1POLB | |
| SCHEMBL24168839 | 0.90 | MTNR1B (0.61) | MTNR1BMTNR1ATGM2ALDH1A1POLB | |
| SCHEMBL20456547 | 0.88 | TGM2 (0.90) | MTNR1BMTNR1ATGM2ALDH1A1POLB | |
| SCHEMBL31069810 | 0.84 | TGM2 (0.66) | TGM2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1383792 | 0.84 | TGM2 (0.66) | TGM2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9017578 | 0.84 | TGM2 (1.00) | TGM2PGRLPAR1LPAR2LPAR3 | |
| SCHEMBL782552 | 0.83 | TGM2 (1.00) | TGM2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14341775 | 0.83 | TGM2 (0.86) | MTNR1BMTNR1ATGM2PGRLPAR1 | |
| SCHEMBL21392902 | 0.83 | TGM2 (0.71) | MTNR1BMTNR1ATGM2LPAR1LPAR2 | |
| SCHEMBL20554816 | 0.83 | ITK (0.53) | MTNR1BMTNR1ATGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090854-A | Aryloxyanilides and related compounds | BRISTOL-MEYERS COMPANY (US) | 2000-07-18 | — | — | US | disclosed |
| WO-1999048859-A1 | ARYLOXYANILIDES AND RELATED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-30 | — | — | WO | disclosed |