Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20262937 | 0.87 | SLC7A5 (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL21597977 | 0.85 | HTR3E (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3838986 | 0.79 | TP53 (0.41) | CYP1A2SMN1; SMN2 | |
| SCHEMBL10549659 | 0.79 | HTR3E (0.36) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL16273850 | 0.79 | ENPP2 (0.52) | CTBP2CYP1A2ALDH1A1CYP3A4NFKB1 | |
| SCHEMBL9506301 | 0.78 | ALDH1A1 (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL21574300 | 0.78 | SLC7A5 (0.41) | SLC7A5CTBP2POLBCYP1A2CYP2C19 | |
| SCHEMBL20321744 | 0.78 | MAOB (0.48) | NOS1ALDH1A1CYP3A4 | |
| SCHEMBL20321551 | 0.78 | HTR3E (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL14884689 | 0.78 | TAAR1 (0.47) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694532-B1 | Perfluoroalkyl sulfide, sulfone, polysulfone and polysulfide diols | CIBA SC HOLDING AG (CH) | 2000-05-31 | — | — | EP | claimed |
| EP-0694532-A1 | Perfluoroalkyl sulfide, sulfone, polysulfone and polysulfide diols | CIBA-GEIGY AG (CH) | 1996-01-31 | — | — | EP | claimed |
| EP-0694532-B1 | Perfluoroalkyl sulfide, sulfone, polysulfone and polysulfide diols | CIBA SC HOLDING AG (CH) | 2000-05-31 | — | — | EP | disclosed |
| US-5708119-A | POLYURETHANES FOR WATERPROOFING AND OIL REPELLENTS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0694532-A1 | Perfluoroalkyl sulfide, sulfone, polysulfone and polysulfide diols | CIBA-GEIGY AG (CH) | 1996-01-31 | — | — | EP | disclosed |