Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 4/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS2 | P35228 | 4/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067663 | 0.87 | TAS1R3 (0.42) | ALDH1A1TAS1R3TAS1R1CNR1CNR2 | |
| SCHEMBL7067333 | 0.81 | CHRM4 (0.36) | ALDH1A1HTTCNR1CNR2MAPT | |
| SCHEMBL7067885 | 0.75 | EGLN1 (0.44) | — | |
| SCHEMBL22262980 | 0.71 | PYGL (0.53) | ALDH1A1NOS3NOS1NOS2POLB | |
| SCHEMBL22262978 | 0.71 | PYGL (0.53) | ALDH1A1NOS3NOS1NOS2POLB | |
| SCHEMBL13515520 | 0.70 | CHRM4 (0.32) | — | |
| SCHEMBL21612140 | 0.69 | NOS3 (0.49) | ALDH1A1HTTNOS3NOS1NOS2 | |
| SCHEMBL28565290 | 0.69 | NOS3 (0.49) | ALDH1A1HTTNOS3NOS1NOS2 | |
| SCHEMBL7471489 | 0.69 | CNR2 (0.30) | CNR2 | |
| SCHEMBL6849521 | 0.69 | NOS3 (0.49) | ALDH1A1HTTNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000336080-A | ISOTHIAZOLECARBOXAMIDES | NIPPON BAYER AGROCHEM CO LTD | 2000-12-05 | — | — | JP | disclosed |