SCHEMBL7471489

SCHEMBL7471489

CC(NC(=O)c1snc(Cl)c1Cl)OCC(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.30
CHRM4 P08173 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13515520 0.79 CHRM4 (0.32) CHRM4
SCHEMBL7090190 0.74 ALDH1A1 (0.31)
SCHEMBL7471498 0.73 ALDH1A1 (0.39)
SCHEMBL7067333 0.72 CHRM4 (0.36) CNR2CHRM4
SCHEMBL7067663 0.70 TAS1R3 (0.42) CNR2
SCHEMBL7067885 0.70 EGLN1 (0.44)
SCHEMBL8153291 0.69 ALDH1A1 (0.46) CNR2
SCHEMBL7067322 0.68 ALDH1A1 (0.36)
SCHEMBL7085349 0.67 OGG1 (0.41)
SCHEMBL7088346 0.67 SMN1; SMN2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1261592-A1 ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES NIHON BAYER AGROCHEM K.K. (JP) 2002-12-04 EP disclosed
WO-2001055124-A1 ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES NIHON BAYER AGROCHEM K.K. (JP) 2001-08-02 WO disclosed