SCHEMBL8153357

SCHEMBL8153357

CC1(C)C2CCC1(C=Cc1ccc(C=CC34CCC(CC3=O)C4(C)C)cc1)C(=O)C2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 3/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
CYP2C19 P33261 3/20 0.36
CYP1A2 P05177 2/20 0.36
CA1 P00915 4/20 0.34
CA2 P00918 4/20 0.34
CA5A P35218 4/20 0.34
CA5B Q9Y2D0 4/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
GPR35 Q9HC97 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20608413 0.94 ALDH1A1 (0.42) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL20455791 0.92 KMT2A (0.44) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL22443203 0.90 ALDH1A1 (0.46) KMT2AALDH1A1MEN1LMNAMAPT
Methylamine SCHEMBL27521765 0.90 MEN1 (0.41) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL25329169 0.83 LMNA (0.44) KMT2AALDH1A1MEN1LMNAMAPT
Acrylamide SCHEMBL27706596 0.82 CYP2C19 (0.40) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL9304228 0.80 ALDH1A1 (0.41) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL9225690 0.78 KMT2A (0.55) KMT2AALDH1A1MEN1LMNAMAPT
SCHEMBL1128206 0.76 KMT2A (0.53) KMT2AALDH1A1MEN1LMNAMAPT
Hydrochloric Acid SCHEMBL5512637 0.72 KMT2A (0.49) KMT2AALDH1A1MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197607-A1 NON-PULVERULENT ANTISUN COMPOSITION COMPRISING A POLAR OIL PHASE AND HYDROPHOBIC SILICA AEROGEL PARTICLES L'OREAL (FR) 2024-06-20 US disclosed
US-20150010601-A1 Non-pulverulent antisun composition comprising a polar oil phase and hydrophobic silica aerogel particles L'OREAL (FR) 2015-01-08 US disclosed
US-6106850-A LIGHT PROTECTIVE COSMETIC/DERMATOLOGICAL COMPOSITION WITH KETONE SULFONIC ACID COMPOSITION SOCIETE L'OREAL S.A. (FR) 2000-08-22 US disclosed
US-5776472-A TOPICAL COSMETIC SOCIETE L'OREAL S.A. (FR) 1998-07-07 US disclosed
US-5730972-A MIXTURE OF SACCHARIDE ESTER OF ASCORBIC ACID AND WATER SOLUBLE SULPHONIC COMPOUND L'OREAL (FR) 1998-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150010601-A1 Non-pulverulent antisun composition comprising a polar oil phase and hydrophobic silica aerogel particles KRT18, CUTA, SMURF1 KMT2A 4095/4885ALDH1A1 4310/4885MEN1 3328/4885
US-20240197607-A1 NON-PULVERULENT ANTISUN COMPOSITION COMPRISING A POLAR OIL PHASE AND HYDROPHOBIC SILICA AEROGEL PARTICLES KRT18, CUTA, SMURF1 KMT2A 4186/4885ALDH1A1 4264/4885MEN1 3244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.