Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RHEB | Q15382 | 2/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069692 | 0.88 | RHEB (0.45) | CYP3A4TSHRRHEBPDE7ACA1 | |
| SCHEMBL1964539 | 0.83 | CYP3A4 (0.56) | CYP3A4TSHRPDE7ACA1CA2 | |
| SCHEMBL632218 | 0.82 | CYP3A4 (0.46) | CYP3A4TSHRRHEBPDE7ACA1 | |
| SCHEMBL9517127 | 0.79 | CYP3A4 (0.52) | CYP3A4TSHRPDE7ACA1CA2 | |
| SCHEMBL4028813 | 0.77 | SLC6A2 (0.38) | CYP3A4TSHRRHEBPDE7ACA1 | |
| SCHEMBL3484572 | 0.77 | ESRRA (0.56) | CYP3A4TSHRRHEBALDH1A1HPGD | |
| SCHEMBL6731188 | 0.76 | ALDH1A1 (0.46) | CYP3A4CA1CA2ALDH1A1HPGD | |
| SCHEMBL25500740 | 0.76 | AR (0.60) | CYP3A4TSHRPDE7AALDH1A1HPGD | |
| SCHEMBL2330113 | 0.76 | MEN1 (0.49) | CYP3A4TSHRPDE7AALDH1A1GAA | |
| SCHEMBL15891019 | 0.76 | SLC6A2 (0.41) | CYP3A4TSHRRHEBPDE7ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700532-B1 | ALIGNMENT LAYER FOR LIQUID CRYSTALS | AVENTIS RES & TECH GMBH & CO (DE) | 2000-03-29 | — | — | EP | disclosed |
| US-5744203-A | POLYMER MIXTURES OF POLYURETHANES, POLYESTERS, POLYIMIDES, POLYCARBONATES AND POLYUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0604885-B1 | Liquid crystal display device | HOECHST AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| US-5656340-A | Liquid crystal display device | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-12 | — | — | US | disclosed |
| EP-0708149-A1 | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |
| EP-0700532-A1 | ALIGNMENT LAYER FOR LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-13 | — | — | EP | disclosed |
| EP-0690334-A2 | Liquid crystal display device | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |
| US-5437813-A | A thin alignment layer comprising an aromatic polyamide-polysiloxane block homo- or copolymer with different content of polysiloxane to adjust optical pretilt angle | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |
| WO-1994028458-A1 | ALIGNMENT LAYER FOR LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | disclosed |
| EP-0604885-A1 | Liquid crystal display device | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-06 | — | — | EP | disclosed |