Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154389 | 0.86 | ADRA2A (0.34) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL8147131 | 0.84 | ADRA2A (0.33) | ADRA2AADRA2BADRA2C | |
| SCHEMBL8639222 | 0.84 | ADRA2A (0.38) | ADRA2AADRA2BADRA2C | |
| SCHEMBL8642271 | 0.80 | GABRA1 (0.34) | — | |
| SCHEMBL8641459 | 0.76 | ADRA2A (0.32) | ADRA2AADRA2BADRA2C | |
| SCHEMBL8639009 | 0.75 | TAAR1 (0.42) | — | |
| SCHEMBL8147129 | 0.71 | ADRA2A (0.33) | ADRA2AADRA2BADRA2C | |
| SCHEMBL7148629 | 0.71 | IDO1 (0.41) | ADRA2AADRA2BADRA2CCYSLTR2CYSLTR1 | |
| SCHEMBL8148412 | 0.69 | TAAR1 (0.33) | — | |
| SCHEMBL8153170 | 0.69 | PGK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000013690-A1 | EXOCYCLIC-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |