Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231169 | 0.84 | LMNA (0.41) | NOS2 | |
| SCHEMBL8149025 | 0.82 | SRC (0.42) | TAAR1HTR2ACHRNB2CHRNA4NOS2 | |
| SCHEMBL8642923 | 0.81 | KDM4E (0.35) | TAAR1 | |
| SCHEMBL8146390 | 0.80 | SCN1A (0.36) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8645901 | 0.80 | HTR2A (0.46) | HTR2ASLC6A2SLC6A4SLC6A3HRH1 | |
| SCHEMBL29025201 | 0.80 | SRC (0.44) | TAAR1HTR2ACHRNB2CHRNA4NOS2 | |
| SCHEMBL8642271 | 0.79 | GABRA1 (0.34) | TAAR1NOS2SLC6A2 | |
| SCHEMBL8153170 | 0.79 | PGK1 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8154367 | 0.75 | ADRA2A (0.34) | — | |
| SCHEMBL8154407 | 0.70 | TRPA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |