Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154374 | 0.87 | BCHE (0.39) | TRPA1PTGS1CACNA1CBCHEACHE | |
| SCHEMBL8639596 | 0.86 | TRPA1 (0.36) | TRPA1PTGS1CACNA1CBCHEACHE | |
| SCHEMBL8148412 | 0.85 | TAAR1 (0.33) | — | |
| SCHEMBL8645772 | 0.85 | TRPA1 (0.36) | TRPA1PTGS1CACNA1CBCHEACHE | |
| SCHEMBL8642923 | 0.81 | KDM4E (0.35) | LMNATYRMAPT | |
| SCHEMBL8146811 | 0.77 | TRPA1 (0.38) | TRPA1LMNA | |
| SCHEMBL8642271 | 0.76 | GABRA1 (0.34) | PTGS1LMNA | |
| SCHEMBL8153118 | 0.76 | BCHE (0.33) | BCHEACHETYRMEN1MAPT | |
| SCHEMBL8639594 | 0.73 | LMNA (0.34) | TRPA1PTGS1CACNA1CBCHEACHE | |
| SCHEMBL8640985 | 0.71 | LMNA (0.33) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000013690-A1 | EXOCYCLIC-PHOSPHOETHANOLAMINES | CLARION PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |