Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147939 | 0.86 | TRPA1 (0.38) | LMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL8148412 | 0.86 | TAAR1 (0.33) | ALDH1A1TAAR1TDP1 | |
| SCHEMBL8154374 | 0.85 | BCHE (0.39) | LMNAKMT2AMEN1 | |
| SCHEMBL8148576 | 0.74 | GABRA1 (0.34) | LMNAKMT2ACA1TSHRTDP1 | |
| SCHEMBL8148760 | 0.72 | LMNA (0.34) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8146811 | 0.72 | TRPA1 (0.38) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8154407 | 0.71 | TRPA1 (0.37) | LMNAKMT2AMEN1 | |
| SCHEMBL8140900 | 0.70 | POLB (0.31) | — | |
| SCHEMBL8148753 | 0.70 | LMNA (0.33) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8149025 | 0.70 | SRC (0.42) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |