SCHEMBL8155124

SCHEMBL8155124

C=C(C)C(=O)OC1CCN(C(=O)/C=C/c2cccc(F)c2C)CC1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.41
ENPP2 Q13822 1/20 0.41
C3AR1 Q16581 1/20 0.41
SMN1; SMN2 Q16637 5/20 0.40
RAB9A P51151 5/20 0.40
NPC1 O15118 4/20 0.40
MAPT P10636 1/20 0.40
ITGAL P20701 2/20 0.38
GPR183 P32249 1/20 0.37
LMNA P02545 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
POLB P06746 1/20 0.36
F2R P25116 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8146027 0.87 KDM4E (0.44) KDM4EHPGDENPP2C3AR1SMN1; SMN2
SCHEMBL23843920 0.83 HPGD (0.47) KDM4EHPGDSMN1; SMN2RAB9ANPC1
SCHEMBL8155120 0.81 KMT2A (0.58) KDM4EHPGDSMN1; SMN2RAB9ANPC1
SCHEMBL8139781 0.80 ALDH1A1 (0.56) HPGDSMN1; SMN2RAB9ANPC1GPR183
SCHEMBL8148369 0.80 L3MBTL1 (0.52) KDM4ESMN1; SMN2RAB9ANPC1MAPT
SCHEMBL8148847 0.79 ITGAL (0.45) ENPP2SMN1; SMN2RAB9AMAPTITGAL
SCHEMBL8141106 0.79 RAB9A (0.59) KDM4EHPGDSMN1; SMN2RAB9ANPC1
SCHEMBL8153364 0.79 KDM4E (0.40) KDM4EHPGDENPP2SMN1; SMN2RAB9A
SCHEMBL8146836 0.79 CCR2 (0.49) KDM4EHPGDSMN1; SMN2RAB9ANPC1
SCHEMBL23843918 0.78 POLB (0.62) HPGDSMN1; SMN2MAPTLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36625-E Linear and cyclic polymers or oligomers having a photoreactive ethene group ROLIC AG (CH) 2000-03-21 US disclosed
US-5539074-A LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS HOFFMANN-LA ROCHE INC. (US) 1996-07-23 US disclosed