Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966397 | 0.91 | IKBKB (0.38) | KDM4EALDH1A1HTR1AHPGDHTR2C | |
| SCHEMBL7962499 | 0.83 | ALDH1A1 (0.35) | KDM4EALDH1A1HPGDIKBKBTNFRSF1A | |
| SCHEMBL7952003 | 0.82 | ALDH1A1 (0.40) | KDM4EALDH1A1HTR1AHPGDHTR2C | |
| SCHEMBL7951999 | 0.82 | ALDH1A1 (0.40) | KDM4EALDH1A1HTR1AHPGDHTR2C | |
| SCHEMBL7964175 | 0.81 | RARA (0.38) | KDM4EALDH1A1HTR1AHPGDHTR2C | |
| SCHEMBL7964173 | 0.81 | RARA (0.38) | KDM4EALDH1A1HTR1AHPGDHTR2C | |
| SCHEMBL7960068 | 0.81 | RARG (0.31) | RARG | |
| SCHEMBL28562986 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1HTR1AHPGDHTR2C | |
| SCHEMBL28562989 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1HTR1AHPGDHTR2C | |
| SCHEMBL8125894 | 0.76 | STING1 (0.39) | IKBKBRARATNFRSF1ARARGF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551034-B1 | Antibiotic cephalosporins having in position 7 a substituted benzyloxyimino radical | HOECHST MARION ROUSSEL INC (FR) | 2000-09-20 | — | — | EP | disclosed |
| EP-1016646-A1 | Intermediates for the preparation of cephalosporines containing on the 7-position a substituted benzyloximino radical | HOECHST MARION ROUSSEL (FR) | 2000-07-05 | — | — | EP | disclosed |
| EP-0551034-A2 | Cephalosporins having in position 7 a benzyloxyimino radical substitute, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1993-07-14 | — | — | EP | disclosed |