Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155643 | 0.91 | KDM4E (0.39) | IKBKBRARAKDM4EALDH1A1HTR1A | |
| SCHEMBL7951999 | 0.84 | ALDH1A1 (0.40) | IKBKBRARAKDM4EALDH1A1HTR1A | |
| SCHEMBL7952003 | 0.84 | ALDH1A1 (0.40) | IKBKBRARAKDM4EALDH1A1HTR1A | |
| SCHEMBL7964173 | 0.83 | RARA (0.38) | IKBKBRARAKDM4EALDH1A1HTR1A | |
| SCHEMBL7964175 | 0.83 | RARA (0.38) | IKBKBRARAKDM4EALDH1A1HTR1A | |
| SCHEMBL7951953 | 0.82 | ALDH1A1 (0.34) | IKBKBRARAKDM4EALDH1A1HPGD | |
| SCHEMBL7951792 | 0.80 | IKBKB (0.30) | IKBKBRARG | |
| SCHEMBL8380440 | 0.76 | PTGER3 (0.56) | KDM4EPTGER3CA1CA2CA4 | |
| SCHEMBL10737031 | 0.75 | KDM4E (0.62) | KDM4EALDH1A1HTR1AHPGDHTR2C | |
| SCHEMBL10737039 | 0.75 | KDM4E (0.62) | KDM4EALDH1A1HTR1AHPGDHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313305-B1 | ANTIBIOTICS, BACTERICIDES | HOECHST MARION ROUSSEL (FR) | 2001-11-06 | — | — | US | disclosed |
| US-5587372-A | BACERICIDES | ROUSSEL UCLAF (FR) | 1996-12-24 | — | — | US | disclosed |