SCHEMBL8155703

SCHEMBL8155703

COc1c(S(=O)(=O)O)ccc2c1C(=O)c1ccc(S(=O)(=O)O)c(OC)c1C2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.49
NPC1 O15118 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPT P10636 5/20 0.41
ALDH1A1 P00352 3/20 0.41
LCK P06239 1/20 0.41
GLA P06280 1/20 0.41
THRB P10828 1/20 0.41
LIMK1 P53667 1/20 0.41
LIMK2 P53671 1/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
EPHX2 P34913 3/20 0.40
PIM1 P11309 2/20 0.37
PGAM1 P18669 1/20 0.37
EGFR P00533 1/20 0.37
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
DUSP3 P51452 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13239419 0.92 SMN1; SMN2 (0.62) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL7269471 0.73 MAPT (0.46) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL6905576 0.72 PGAM1 (0.53) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL28115561 0.72 RAB9A (0.55) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL9065513 0.72 RAB9A (0.40) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL18700944 0.72 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1GLAMEN1KMT2A
SCHEMBL30354040 0.71 PDE4B (0.45) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL28021384 0.71 RAB9A (0.53) RAB9ANPC1SMN1; SMN2MAPTALDH1A1
SCHEMBL24094066 0.70 SMN1; SMN2 (0.35) SMN1; SMN2MAPTALDH1A1GLAMEN1
SCHEMBL18700993 0.70 TET2 (0.36) ALDH1A1GLAMEN1KMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733473-B1 Multi-layered film TEIJIN LTD (JP) 2000-09-27 EP disclosed
US-5879813-A POLYOLEFIN LAYER, POLYESTER OR POLYPHENYLENE SULFIDE LAYER, QUATERNARY PHOSPHONIUM SALT OF SULFONIC ACID; UNIFORMITY, EASILY PEELED FILM TEIJIN LIMITED (JP) 1999-03-09 US disclosed
EP-0733473-A2 Multi-layered film TEIJIN LIMITED (JP) 1996-09-25 EP disclosed