Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17169199 | 0.85 | ALDH1A1 (0.38) | MAPTTDP1ALDH1A1KMT2ALMNA | |
| SCHEMBL668439 | 0.84 | HTR6 (0.47) | MAPTALDH1A1KMT2ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1796557 | 0.82 | HTR6 (0.46) | MAPTALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11564635 | 0.81 | CNR2 (0.44) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL17705867 | 0.80 | CA12 (0.50) | MAPTTDP1ALDH1A1KMT2ALMNA | |
| SCHEMBL29785793 | 0.80 | TRPV4 (0.55) | MAPTTDP1ALDH1A1KMT2ALMNA | |
| SCHEMBL4207227 | 0.80 | CA2 (0.49) | MAPTTDP1ALDH1A1KMT2ALMNA | |
| SCHEMBL2494766 | 0.80 | TRPV4 (0.55) | MAPTTDP1ALDH1A1KMT2ALMNA | |
| SCHEMBL27803022 | 0.79 | TRPV4 (0.36) | MAPTTDP1ALDH1A1KMT2ALMNA | |
| SCHEMBL17303412 | 0.78 | POLB (0.46) | MAPTTDP1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649613-B1 | Integrin inhibitors | MERCK PATENT GMBH (DE) | 2003-11-18 | — | — | US | disclosed |