SCHEMBL8156347

SCHEMBL8156347

c1nnc(Oc2nncs2)s1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.42
CYP1A2 P05177 1/20 0.37
TSHR P16473 1/20 0.37
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6264790 0.79 LTA4H (0.44) TSHR
SCHEMBL2585574 0.68 CA2 (0.44) FBP1TSHRCA1CA2CA4
SCHEMBL2003065 0.61
SCHEMBL14891491 0.61
SCHEMBL5457200 0.59 FBP1 (1.00) FBP1CYP1A2TSHRCA1CA2
SCHEMBL8878345 0.59 FBP1 (0.70) FBP1CYP1A2TSHRCA1CA2
SCHEMBL11119985 0.59
SCHEMBL10949129 0.57
SCHEMBL10089552 0.56
SCHEMBL193919 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0779331-B1 1,3,4-Thiadiazole ether curing systems for chlorine containing polymers VANDERBILT CO R T (US) 2000-05-03 EP disclosed
EP-0779331-A2 1,3,4-Thiadiazole ether curing systems for chlorine containing polymers R.T. VANDERBILT COMPANY, Inc. (US) 1997-06-18 EP disclosed