Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.44 |
| ▸ | CA1 | P00915 | 12/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 12/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634316 | 0.68 | — | — | |
| SCHEMBL5097249 | 0.68 | CA2 (0.48) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL2591217 | 0.68 | ALDH1A1 (0.38) | CA2CA1CA9FBP1TSHR | |
| SCHEMBL8156347 | 0.68 | FBP1 (0.42) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL2399941 | 0.66 | — | — | |
| SCHEMBL3165386 | 0.65 | ALDH1A1 (0.39) | CA2CA1CA9FBP1TSHR | |
| SCHEMBL15271949 | 0.64 | CA2 (0.37) | CA2CA1CA9STS | |
| SCHEMBL27270091 | 0.60 | — | — | |
| SCHEMBL29395571 | 0.58 | CA1 (0.40) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL6264790 | 0.57 | LTA4H (0.44) | MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123135-A1 | Methods To Identify Modulators of TAS2R48 Receptors | GIVAUDAN SA (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130115624-A1 | Methods To Identify Modulators | GIVAUDAN S.A. (CH) | 2013-05-09 | — | — | US | disclosed |
| EP-2567231-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| EP-2567229-A1 | METHODS TO IDENTIFY MODULATORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138455-A1 | METHODS TO IDENTIFY MODULATORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011138456-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |