Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.57 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.57 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258192 | 1.00 | ALDH1A1 (0.58) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL5485588 | 0.94 | LMNA (0.61) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL2820683 | 0.94 | LMNA (0.61) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| Acetic Acid SCHEMBL8324881 | 0.89 | LMNA (0.56) | ALDH1A1LMNASMN1; SMN2HTTPLAU | |
| SCHEMBL11126514 | 0.88 | ALDH1A1 (0.58) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL30440860 | 0.88 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL5873775 | 0.88 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8178335 | 0.88 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8327761 | 0.86 | ALDH1A1 (0.59) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL30576720 | 0.86 | PRSS1 (0.71) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028102-A | Anticonvulsant drugs and pharmaceutical compositions thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM | 2000-02-22 | — | — | US | disclosed |