Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.57 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.57 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156969 | 1.00 | ALDH1A1 (0.58) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL5485588 | 0.94 | LMNA (0.61) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL2820683 | 0.94 | LMNA (0.61) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| Acetic Acid SCHEMBL8324881 | 0.89 | LMNA (0.56) | ALDH1A1LMNASMN1; SMN2HTTPLAU | |
| SCHEMBL11126514 | 0.88 | ALDH1A1 (0.58) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL30440860 | 0.88 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL5873775 | 0.88 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8178335 | 0.88 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8327761 | 0.86 | ALDH1A1 (0.59) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL30576720 | 0.86 | PRSS1 (0.71) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2805732-B1 | Polymer-drug conjugates for the treatment of amyloidosis | FUNDACIÓN COMUNIDAD VALENCIANA CT DE INVESTIGACIÓN PRINCIPE FELIPE (ES) | 2016-09-28 | — | — | EP | disclosed |
| US-20160114055-A1 | POLYMER DRUG CONJUGATES FOR THE TREATMENT OF AMYLOIDOSIS | FUNDACION DE LA COMUNIDAD VALENCIANA "CENTRO DE INVESTIGACIONES PRINCIPE FELIPE" (ES) | 2016-04-28 | — | — | US | disclosed |
| EP-2805732-A1 | Polymer-drug conjugates for the treatment of amyloidosis | Fundación Comunidad Valenciana Centro de Investigación Principe Felipe (ES) | 2014-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114055-A1 | POLYMER DRUG CONJUGATES FOR THE TREATMENT OF AMYLOIDOSIS | FAP, MAPT, TTR | ALDH1A1 2105/4885PRSS1 3015/4885TPSAB1 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.