Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231456 | 0.98 | ACMSD (0.47) | ACMSDAGXTLTA4HEPHX2PRKCI | |
| SCHEMBL27988774 | 0.94 | CYP4F2 (0.49) | ACMSDAGXTLTA4HEPHX2PRKCI | |
| SCHEMBL3705276 | 0.92 | BCHE (0.48) | ACMSDAGXTPRKCITDP1GPR84 | |
| SCHEMBL5865105 | 0.88 | TDP1 (0.62) | ACMSDAGXTPRKCITDP1GPR84 | |
| Biphenyl SCHEMBL27528312 | 0.87 | TDP1 (0.61) | LTA4HEPHX2TDP1IGF1RALOX15 | |
| SCHEMBL19226923 | 0.86 | GRIN2D (0.46) | AGXTLTA4HEPHX2TDP1IGF1R | |
| SCHEMBL5362418 | 0.85 | AGXT (0.54) | ACMSDAGXTPRKCICYP4F2CYP4A11 | |
| SCHEMBL612967 | 0.85 | PTGES (0.47) | ACMSDLTA4HEPHX2TDP1CYP4F2 | |
| SCHEMBL378731 | 0.85 | HSD17B1 (0.52) | ACMSDCYP4F2CYP4A11 | |
| SCHEMBL29618101 | 0.83 | SIGMAR1 (0.52) | AGXTIGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146020-B | Method for synthesizing 1,3-diphenyl-1-propanol compound | UNIV JILIN | 2013-09-18 | — | — | CN | claimed |
| CN-102146020-A | Method for synthesizing 1,3-diphenyl-1-propanol compound | UNIV JILIN | 2011-08-10 | — | — | CN | claimed |
| CN-119285657-A | Method for synthesizing alkyl borate compound by taking allyl alcohol as substrate | 河南大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-108117534-B | Benzo-oxygenated aliphatic cyclomethylamines | 华东理工大学 | 2021-02-05 | — | — | CN | disclosed |
| US-10829464-B2 | Benzoheterocyclic alkylamine compounds and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| CN-108084125-B | Benzoheterocyclylalkylamines and their use | 华东理工大学 | 2020-08-18 | — | — | CN | disclosed |
| US-20190315703-A1 | BENZOHETEROCYCLIC ALKYLAMINE COMPOUNDS AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-10-17 | — | — | US | disclosed |
| EP-3546454-A1 | BENZOHETEROCYCLYL ALKYLAMINE COMPOUND AND USE THEREOF | East China University of Science and Technology (CN) | 2019-10-02 | — | — | EP | disclosed |
| EP-2168944-B1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-11 | — | — | EP | disclosed |
| EP-2168944-B1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-11 | — | — | EP | disclosed |
| CN-102146020-B | Method for synthesizing 1,3-diphenyl-1-propanol compound | UNIV JILIN | 2013-09-18 | — | — | CN | disclosed |
| US-20030134841-A1 | Succinoylamino lactams as inhibitors of A-beta protein production | OLSON RICHARD E (US) | 2003-07-17 | — | — | US | disclosed |
| US-20020159947-A1 | Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging | LANTHEUS MEDICAL IMAGING, INC. | 2002-10-31 | — | — | US | disclosed |
| US-6331408-B1 | CONTACTING A POTENTIAL INHIBITOR OF BETA-AMYLOID PRODUCTION AND TAGGED INHIBITOR OF BETA-AMYLOID PRODUCTION WITH AT MACROMOLECULE INVOLVED IN PROCESSING OF AMYLOID PRECURSOR PROTEIN; SEPARATING TAGGED INHIBITOR, DETERMINING | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2001-12-18 | — | — | US | disclosed |
| WO-2001087354-A2 | USE OF SMALL MOLECULE RADIOLIGANDS FOR DIAGNOSTIC IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |
| EP-1129355-A1 | USE OF RADIOLIGANDS TO SCREEN INHIBITORS OF AMYLOID-BETA PEPTIDE PRODUCTION | Du Pont Pharmaceuticals Company (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-1102752-A1 | SUCCINOYLAMINO LACTAMS AS INHIBITORS OF A BETA PROTEIN PRODUCTION | Du Pont Pharmaceuticals Company (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000028331-A1 | USE OF RADIOLIGANDS TO SCREEN INHIBITORS OF AMYLOID-BETA PEPTIDE PRODUCTION | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-05-18 | — | — | WO | disclosed |
| WO-2000007995-A1 | SUCCINOYLAMINO LACTAMS AS INHIBITORS OF Aβ PROTEIN PRODUCTION | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-02-17 | — | — | WO | disclosed |
| CN-1106003-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL MYERS SQIUBB COMPANY (US) | 1995-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829464-B2 | Benzoheterocyclic alkylamine compounds and use thereof | AADAC, AAAS, NISCH | ACMSD 71/4885AGXT 920/4885LTA4H 123/4885 |
| US-20020159947-A1 | Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging | APP, BACE1, BACE2 | ACMSD 4339/4885AGXT 2091/4885LTA4H 2678/4885 |
| US-20190315703-A1 | BENZOHETEROCYCLIC ALKYLAMINE COMPOUNDS AND USE THEREOF | AADAC, AAAS, NISCH | ACMSD 71/4885AGXT 920/4885LTA4H 123/4885 |
| US-20030134841-A1 | Succinoylamino lactams as inhibitors of A-beta protein production | APH1A, BACE1, APP | ACMSD 571/4885AGXT 355/4885LTA4H 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.