Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907292 | 0.82 | TDP1 (0.46) | TDP1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL10888683 | 0.81 | ALDH1A1 (0.41) | TDP1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL473378 | 0.78 | TDP1 (0.52) | TDP1ALDH1A1CYP3A4TSHRLMNA | |
| Hydrochloric Acid SCHEMBL473354 | 0.76 | TDP1 (0.50) | TDP1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL27666006 | 0.74 | TDP1 (0.43) | TDP1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL4128163 | 0.74 | KDM4E (0.55) | ALDH1A1TSHRHSD17B10L3MBTL1RECQL | |
| SCHEMBL10891142 | 0.73 | POLB (0.46) | ALDH1A1CYP3A4LMNAKDM4EKMT2A | |
| SCHEMBL3121850 | 0.73 | PGR (0.30) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL7274967 | 0.72 | SIGMAR1 (0.50) | ADRA2AKCNH2KDM4E | |
| SCHEMBL10936696 | 0.72 | TSHR (0.43) | ALDH1A1TSHRLMNATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024170-A1 | CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2000-08-02 | — | — | EP | disclosed |