Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | AQP4 | P55087 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963857 | 0.94 | KDM4E (0.61) | RAB9ANPC1MEN1KMT2AAQP4 | |
| SCHEMBL3379803 | 0.82 | AQP4 (0.70) | RAB9ANPC1MEN1KMT2AAQP4 | |
| SCHEMBL14328939 | 0.79 | TSHR (0.60) | RAB9ANPC1MEN1KMT2AAQP4 | |
| SCHEMBL5407305 | 0.78 | NR3C1 (0.55) | RAB9ANPC1AQP4KDM4E | |
| SCHEMBL7348856 | 0.77 | LMNA (0.62) | RAB9ANPC1MEN1KMT2AAQP4 | |
| SCHEMBL8554147 | 0.77 | LMNA (0.65) | RAB9ANPC1MEN1KMT2AAQP4 | |
| SCHEMBL6799313 | 0.75 | RAB9A (0.60) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL14807588 | 0.73 | TOP1 (0.74) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL5971771 | 0.73 | KMT2A (0.65) | NPC1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL23417709 | 0.72 | KDM4E (0.54) | RAB9ANPC1MEN1KMT2AAQP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063800-A | Modulators of molecules with phosphotyrosine recognition units | NOVO NORDISK A/S (DK) | 2000-05-16 | — | — | US | disclosed |
| US-5958957-A | PROTEIN TYROSINE PHOSPHATASES, PROTEINS WITH SRC-MONOLOGY 2-DOMAINS; ANTICARCINOGENIC,-TUMOR AND DIABETIC AGENTS; PURIFICATION OF PROTEINS AND GLYCOPROTEINS; MEDICAL DIAGNOSIS | NOVO NORDISK A/S (DK) | 1999-09-28 | — | — | US | disclosed |