Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144342 | 0.92 | CYP4F2 (0.62) | CYP4F2CYP4A11SLC7A5ALDH1A1LMNA | |
| SCHEMBL2490447 | 0.82 | CYP4A11 (0.54) | CYP4F2CYP4A11CPA3FOLH1CYP1A2 | |
| SCHEMBL15522691 | 0.79 | CYP4F2 (0.54) | CYP4F2CYP4A11SLC7A5ALDH1A1LMNA | |
| SCHEMBL10327379 | 0.79 | CPA3 (0.50) | CPA3FOLH1CYP1A2LAP3ERAP2 | |
| SCHEMBL8158289 | 0.79 | CYP4F2 (0.61) | CYP4F2CYP4A11SLC7A5ALDH1A1LMNA | |
| SCHEMBL15522771 | 0.78 | CYP4F2 (0.53) | CYP4F2CYP4A11SLC7A5ALDH1A1LMNA | |
| SCHEMBL6176616 | 0.78 | MMP3 (0.60) | CPA3CYP1A2ALDH1A1LDHAMMP3 | |
| SCHEMBL8150696 | 0.78 | CYP4F2 (0.55) | CYP4F2CYP4A11SLC7A5ALDH1A1LMNA | |
| SCHEMBL26152591 | 0.77 | CYP4F2 (0.51) | CYP4F2CYP4A11SLC7A5ALDH1A1LMNA | |
| SCHEMBL23582837 | 0.77 | CYP4F2 (0.68) | CYP4F2CYP4A11ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217063-B2 | Lactam-substituted dicarboxylic acids and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-07-10 | — | — | US | disclosed |
| EP-2142504-B1 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | Bayer Pharma AG (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20100197680-A1 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-05 | — | — | US | disclosed |
| WO-2008119457-A2 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197680-A1 | LACTAM-SUBSTITUTED DICARBOXYLIC ACIDS AND USE THEREOF | DDO, DDC, BCAT2 | CYP4F2 672/4885CYP4A11 2160/4885SLC7A5 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.