Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MPI | P34949 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981252 | 0.71 | L3MBTL1 (0.38) | L3MBTL1MAPTKMT2AMPIKDM4E | |
| SCHEMBL8439166 | 0.67 | ALDH1A1 (0.40) | MAPTKMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL9724293 | 0.66 | GAA (0.43) | L3MBTL1GAAMAPTKMT2AKDM4E | |
| SCHEMBL11908675 | 0.65 | CCR1 (0.53) | L3MBTL1ELANEKMT2AKDM4EALDH1A1 | |
| SCHEMBL5639160 | 0.65 | MAPT (0.48) | L3MBTL1GAAMAPTKMT2AKDM4E | |
| SCHEMBL23904838 | 0.64 | CA12 (0.46) | L3MBTL1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28482048 | 0.64 | CA12 (0.49) | L3MBTL1ELANEALOX5GAAMAPT | |
| SCHEMBL16505732 | 0.63 | BRD4 (0.60) | L3MBTL1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL31453471 | 0.63 | BRD4 (0.60) | L3MBTL1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL12873479 | 0.63 | ALOX5 (0.43) | ELANEALOX5GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027351-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999021860-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 1999-05-06 | — | — | WO | disclosed |