Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981149 | 0.72 | ALDH1A1 (0.38) | ALDH1A1EGLN1TSHRPOLBPDE10A | |
| Hydrochloric Acid SCHEMBL9438985 | 0.61 | MAPT (0.68) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| Phenanthroline SCHEMBL28097109 | 0.60 | LMNA (0.73) | ALDH1A1EGLN1TSHRPOLBPDE10A | |
| SCHEMBL963924 | 0.60 | LMNA (0.50) | ALDH1A1TSHRSLC40A1KDM4EMEN1 | |
| SCHEMBL2809758 | 0.60 | TSHR (0.89) | ALDH1A1TSHRPOLBKDM4EMEN1 | |
| SCHEMBL5599951 | 0.60 | TSHR (0.89) | ALDH1A1TSHRPOLBKDM4EMEN1 | |
| SCHEMBL9928660 | 0.59 | CYP3A4 (0.66) | ALDH1A1TSHRLMNACYP3A4CYP2D6 | |
| SCHEMBL12934580 | 0.59 | PSMD14 (0.48) | TSHRCYP3A4 | |
| Phenanthroline SCHEMBL4881417 | 0.59 | LMNA (0.70) | ALDH1A1EGLN1TSHRPOLBKDM4E | |
| Phenanthroline SCHEMBL22401704 | 0.59 | LMNA (0.70) | ALDH1A1EGLN1TSHRPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916898-A | ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-06-29 | — | — | US | disclosed |