Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547323 | 0.83 | MAPT (0.42) | MAPTALDH1A1KMT2ATDP1HTT | |
| SCHEMBL8554180 | 0.82 | GLO1 (0.51) | MAPTALDH1A1KMT2AHTTMAPK1 | |
| SCHEMBL8157290 | 0.81 | MAPT (0.41) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL8158569 | 0.79 | TDP1 (0.43) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL8555523 | 0.79 | TGM2 (0.42) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL8552324 | 0.78 | MAPT (0.48) | MAPTGAAALDH1A1KMT2AHTT | |
| SCHEMBL8552120 | 0.75 | RAB9A (0.35) | MAPTGAAALDH1A1KMT2AHTT | |
| SCHEMBL4019892 | 0.74 | ALDH1A1 (0.51) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL4019895 | 0.74 | ALDH1A1 (0.51) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL8548079 | 0.73 | CA1 (0.41) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |