SCHEMBL8159757

SCHEMBL8159757

C=CCCCCCC[SiH2]C=C(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
MAPT P10636 3/20 0.38
ABCC4 O15439 1/20 0.38
ALDH1A1 P00352 4/20 0.37
LMNA P02545 2/20 0.37
LPAR3 Q9UBY5 2/20 0.33
USP2 O75604 2/20 0.33
CYP3A4 P08684 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RECQL P46063 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33
HPGD P15428 1/20 0.33
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7642200 0.75 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL1824796 0.75 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL7641099 0.75 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL7645599 0.75 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL383195 0.75 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL7643446 0.75 TSHR (0.52) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL3683778 0.73 TSHR (0.50) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL383448 0.72 TSHR (0.48) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL9154897 0.71 TSHR (0.43) TSHRMAPTABCC4ALDH1A1LMNA
SCHEMBL20536321 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768686-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies, LLC (US) 2021-01-27 EP claimed
EP-3768687-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP claimed
US-20210002315-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US claimed
US-20210002308-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US claimed
CN-112074525-A Silicon-terminated organometallic compounds and methods for making the same 陶氏环球技术有限责任公司 2020-12-11 CN claimed
CN-112004818-A Silicon-terminated organometallic compounds and methods of making the same 陶氏环球技术有限责任公司 2020-11-27 CN claimed
WO-2019182988-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO claimed
WO-2019182983-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO claimed
EP-3768686-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies, LLC (US) 2021-01-27 EP disclosed
EP-3768687-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
EP-3768733-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
US-20210017311-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2021-01-21 US disclosed
US-20210002315-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US disclosed
US-20210002308-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US disclosed
US-5407970-A Peel adhesion, cohesive strength at elevated temperatures MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-18 US disclosed
EP-0416921-B1 Radiation curable polyolefin pressure-sensitive adhesive MINNESOTA MINING & MFG (US) 1995-01-18 EP disclosed
EP-0620258-A2 Radiation-curable poly(alpha-olefin) adhesives containing pendant olefinic functionality MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-10-19 EP disclosed
US-5209971-A Radiation curable polyolefin pressure sensitive adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-11 US disclosed
US-5112882-A Alpha-olefin polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-05-12 US disclosed
EP-0416921-A1 Radiation curable polyolefin pressure-sensitive adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-03-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002308-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME SCAMP2, SOD1, SCLY TSHR 4805/4885MAPT 4501/4885ABCC4 1471/4885
US-20210002315-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME SIK1, SIK2, MCM7 TSHR 4850/4885MAPT 1981/4885ABCC4 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.