Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | IL6ST | P40189 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821135 | 0.84 | PSEN1 (0.40) | GPR84L3MBTL1ICMTIL6STPOLB | |
| SCHEMBL3170619 | 0.83 | ALDH1A1 (0.39) | GPR84LMNAPKML3MBTL1CREBBP | |
| SCHEMBL27799940 | 0.83 | CDC25A (0.42) | ICMTIL6ST | |
| SCHEMBL20855303 | 0.82 | GPR84 (0.43) | GPR84LMNAHTR2AOPRM1OPRL1 | |
| SCHEMBL27174180 | 0.82 | HTR2A (0.59) | HTR2AOPRM1OPRL1 | |
| SCHEMBL25295551 | 0.80 | HTR6 (0.55) | — | |
| SCHEMBL22955211 | 0.76 | PLK1 (0.47) | LMNAL3MBTL1CREBBPNR4A2POLB | |
| Isothiocyanate SCHEMBL28444831 | 0.74 | KEAP1 (0.38) | GPR84LMNAL3MBTL1HTR2AOPRM1 | |
| SCHEMBL28369302 | 0.74 | S1PR2 (0.53) | LMNAL3MBTL1POLB | |
| SCHEMBL22955597 | 0.73 | ALDH1A1 (0.56) | LMNAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150395-A | CYCLIN DEPENDENT KINASE (CDK) INHIBITORS INHIBIT THE GROWTH OF ESTROGEN-DEPENDENT OR INDEPENDENT BREAST CANCER CELLS AND OTHER TYPES OF CANCER CELLS THAT REVEAL INDUCED CDK6; ANTIESTROGENS; ANTITUMOR AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-11-21 | — | — | US | claimed |