Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.58 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MLYCD | O95822 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ESRRG | P62508 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258710 | 0.94 | NPC1 (0.60) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL8408143 | 0.86 | SPHK2 (0.63) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL8170471 | 0.83 | ESRRG (0.63) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL8322962 | 0.82 | SPHK2 (0.58) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL8162229 | 0.82 | NPC1 (0.58) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL27308168 | 0.80 | NPC1 (0.73) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL305562 | 0.80 | GAA (0.65) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL23193945 | 0.80 | EPHX2 (0.58) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL1927473 | 0.80 | RAB9A (0.67) | HDAC2HDAC8HDAC6RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6421806 | 0.78 | GAA (0.63) | HDAC2HDAC8HDAC6RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057345-A | ANTAGONISTS OF THE PAIN ENHANCING EFFECTS OF E-TYPE PROSTAGLANDINS; USED IN PAIN RELIEF | ZENECA LIMITED (GB) | 2000-05-02 | — | — | US | claimed |