Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL28073453 | 0.84 | PTGS2 (0.61) | PTGS2MAPTSMN1; SMN2ALDH1A1 | |
| Naphthalene SCHEMBL28289269 | 0.84 | TP53 (0.58) | LMNANPSR1PTGS2CYP2D6SRC | |
| Biphenyl SCHEMBL1774586 | 0.84 | PTGS2 (0.61) | PTGS2MAPTSMN1; SMN2ALDH1A1 | |
| Methylmalonic Acid SCHEMBL27861389 | 0.83 | TP53 (0.50) | LMNANPSR1PTGS2MAPTXBP1 | |
| Methylmalonic Acid SCHEMBL27707735 | 0.82 | LMNA (0.50) | LMNANPSR1PTGS2MAPTXBP1 | |
| Naphthalene SCHEMBL27680243 | 0.82 | ALDH1A1 (0.44) | LMNANPSR1PTGS2CYP2D6SRC | |
| Naphthalene SCHEMBL699807 | 0.82 | TAAR1 (0.46) | LMNANPSR1PTGS2CYP2D6SRC | |
| Naphthalene SCHEMBL699808 | 0.82 | TAAR1 (0.46) | LMNANPSR1PTGS2CYP2D6SRC | |
| Methylmalonic Acid SCHEMBL27707757 | 0.82 | CA12 (0.55) | LMNANPSR1PTGS2MAPTXBP1 | |
| Naphthalene SCHEMBL9080630 | 0.80 | PTGS2 (0.42) | LMNANPSR1PTGS2MAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071846-A | OLEFIN POLYMERIZATION CATALYST WHICH ALLOWS A POLYOLEFIN TO HAVE HIGH STEREOREGULARITY AND HIGH POLYMERIZATION ACTIVITY; SOLID TITANIUM CATALYST COMPONENT COMPRISES A MAGNESIUM ATOM, TITANIUM ATOM, HALOGEN ATOM AND ELECTRON DONOR | TOKUYAMA CORPORATION (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0739907-B1 | An olefin polymerization catalyst and a polyolefin production method | TOKUYAMA CORP (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0739907-A1 | An olefin polymerization catalyst and a polyolefin production method | TOKUYAMA CORPORATION (JP) | 1996-10-30 | — | — | EP | disclosed |