Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.43 |
| ▸ | MC3R | P41968 | 3/20 | 0.43 |
| ▸ | MC5R | P33032 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8163602 | 0.94 | MMP2 (0.42) | MC4RMC3RMC5RPPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL8165236 | 0.89 | MC4R (0.43) | MC4RMC3RMC5RPPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL8163599 | 0.83 | LTA4H (0.44) | MC4RMC3RMC5RPPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL7860829 | 0.83 | LNPEP (0.44) | MC4RMC3RMC5RPPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL8170100 | 0.81 | LTA4H (0.41) | MC4RMC3RPPARGPPARAMMP2 | |
| Trifluoroacetic Acid SCHEMBL8174490 | 0.81 | MC4R (0.44) | MC4RMC3RMC5RCTSCMMP2 | |
| Ether SCHEMBL8163591 | 0.80 | CYP3A4 (0.39) | MC4RMC3RMC5RPPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL7860786 | 0.79 | KDM4E (0.43) | PPARGPPARAMMP2PLAULTA4H | |
| SCHEMBL8170011 | 0.78 | ERAP2 (0.40) | MC4RMC3RMC5RPPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL7860864 | 0.78 | ERAP2 (0.42) | MC4RMC3RMC5RCTSCMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |