Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736912 | 0.86 | FPR2 (0.49) | ADRA2AADRA2BADRA2CALDH1A1KMT2A | |
| SCHEMBL6952503 | 0.79 | MTOR (0.44) | ADRA2AADRA2BADRA2CKDM4EALDH1A1 | |
| SCHEMBL954734 | 0.79 | CHRM2 (0.45) | ADRA2AADRA2BADRA2CTSHRLMNA | |
| SCHEMBL6204544 | 0.78 | MGAM (0.49) | ADRA2AADRA2BADRA2CHSD17B10MEN1 | |
| SCHEMBL19019814 | 0.77 | FFAR1 (0.50) | ADRA2AADRA2BADRA2CALDH1A1KMT2A | |
| SCHEMBL953334 | 0.76 | CHRM2 (0.43) | ADRA2AADRA2BADRA2CMTORADK | |
| SCHEMBL109205 | 0.76 | LMNA (0.53) | BRD4CYP2C9KDM4EALDH1A1ALB | |
| SCHEMBL6934137 | 0.76 | TAAR1 (0.52) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL9386046 | 0.76 | NISCH (0.44) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL10956049 | 0.75 | HRH1 (0.56) | ADRA2AADRA2BADRA2CCYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011723-A1 | 88KDA TUMORIGENIC GROWTH FACTOR AND ANTAGONISTS | Serrero, Ginette (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998052607-A1 | 88KDA TUMORIGENIC GROWTH FACTOR AND ANTAGONISTS | SERRERO GINETTE (US) | 1998-11-26 | — | — | WO | disclosed |