Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SI | P14410 | 3/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165342 | 0.78 | ADRA2A (0.48) | RAB9AMAPTKMT2AMEN1FPR2 | |
| SCHEMBL6952503 | 0.73 | MTOR (0.44) | ADRA2AADRA2BADRA2C | |
| SCHEMBL9386046 | 0.73 | NISCH (0.44) | ADRA2AADRA2BADRA2C | |
| SCHEMBL6201073 | 0.72 | CYP19A1 (0.53) | MGAMGAASIMGAM2PDPK1 | |
| SCHEMBL955399 | 0.72 | ADRA2B (0.47) | L3MBTL1FPR2ADRA2AADRA2BADRA2C | |
| SCHEMBL30620467 | 0.71 | PDPK1 (0.60) | GAAPDPK1MAPTL3MBTL1POLB | |
| SCHEMBL29110668 | 0.71 | PDPK1 (0.60) | GAAPDPK1MAPTL3MBTL1POLB | |
| SCHEMBL28615060 | 0.70 | POLB (0.59) | PDPK1MAPTL3MBTL1POLBKMT2A | |
| SCHEMBL954734 | 0.70 | CHRM2 (0.45) | ADRA2AADRA2BADRA2C | |
| SCHEMBL6934137 | 0.70 | TAAR1 (0.52) | ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |