SCHEMBL8165404

SCHEMBL8165404

C=Cc1ccccc1COc1ccc(C(C)(c2ccc(OCc3ccccc3C=C)cc2)c2ccc(OCc3ccccc3C=C)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
TMPRSS6 Q8IU80 1/20 0.36
ST14 Q9Y5Y6 1/20 0.36
MAOB P27338 8/20 0.36
MAOA P21397 2/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
APP P05067 1/20 0.36
PTPRC P08575 1/20 0.36
PTPN1 P18031 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8163506 0.82 F2 (0.41) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL11215052 0.82 SMN1; SMN2 (0.46) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL8166262 0.80 MAOB (0.42) MAOBSMN1; SMN2ALDH1A1KMT2ANPC1
SCHEMBL8625765 0.77 ALDH1A1 (0.51) MAOBMAOAPTPRCPTPN1SMN1; SMN2
SCHEMBL20855968 0.77 CYSLTR1 (0.44) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL1539554 0.76 APP (0.45) MAOBAPPSMN1; SMN2TP53POLB
SCHEMBL21156386 0.74 ALDH1A1 (0.36) ALDH1A1
SCHEMBL9650220 0.74 PPARG (0.49) MAOBAPPSMN1; SMN2NPC1RAB9A
SCHEMBL9155982 0.72 RAB9A (0.56) MAOBMAOAPTPN1SMN1; SMN2ALDH1A1
SCHEMBL8165410 0.72 APP (0.51) MAOBAPPPTPRCPTPN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890615-B1 High temperature crosslinkable liquid crystalline polyester compositions DAINIPPON INK & CHEMICALS (JP) 2000-05-03 EP claimed
EP-0890615-A1 High temperature crosslinkable liquid crystalline polyester compositions DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-01-13 EP claimed
EP-0890615-B1 High temperature crosslinkable liquid crystalline polyester compositions DAINIPPON INK & CHEMICALS (JP) 2000-05-03 EP disclosed
EP-0890615-A1 High temperature crosslinkable liquid crystalline polyester compositions DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-01-13 EP disclosed