SCHEMBL8166262

SCHEMBL8166262

C=Cc1ccccc1COc1ccc(CC)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.42
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
SOD1 P00441 1/20 0.40
MAPT P10636 4/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KMT2A Q03164 1/20 0.39
CHRNA7 P36544 1/20 0.39
HSP90AA1 P07900 1/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539478 0.84 MAPT (0.50) MAOBRXRARXRBL3MBTL1TDP1
SCHEMBL20855968 0.84 CYSLTR1 (0.44) MAOBMAPTLMNAFFAR1FFAR4
SCHEMBL8163506 0.83 F2 (0.41) MAOBTDP1SMN1; SMN2NPC1RAB9A
SCHEMBL11215052 0.83 SMN1; SMN2 (0.46) MAOBALDH1A1LMNASMN1; SMN2NPC1
SCHEMBL8165404 0.80 F2 (0.36) MAOBALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL9155982 0.80 RAB9A (0.56) MAOBTDP1MAPTALDH1A1LMNA
SCHEMBL8625765 0.78 ALDH1A1 (0.51) MAOBL3MBTL1TDP1MAPTALDH1A1
SCHEMBL8276185 0.78 RXRA (0.42) MAOBRXRARXRBL3MBTL1TDP1
SCHEMBL17217693 0.77 CYP2A6 (0.33)
SCHEMBL17217690 0.77 CYP2A6 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890615-B1 High temperature crosslinkable liquid crystalline polyester compositions DAINIPPON INK & CHEMICALS (JP) 2000-05-03 EP disclosed