Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 10/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602449 | 0.88 | MAPT (0.51) | MAPTL3MBTL1HPGDMAPK1REN | |
| SCHEMBL1751411 | 0.85 | MAPT (0.49) | MAPTL3MBTL1HPGDMAPK1REN | |
| SCHEMBL663105 | 0.84 | REN (0.49) | MAPTL3MBTL1HPGDMAPK1REN | |
| SCHEMBL12601506 | 0.83 | REN (0.48) | MAPTL3MBTL1HPGDMAPK1REN | |
| SCHEMBL5795265 | 0.83 | MAPT (0.58) | MAPTL3MBTL1HPGDMAPK1REN | |
| SCHEMBL10289213 | 0.82 | REN (0.50) | MAPTL3MBTL1HPGDMAPK1REN | |
| SCHEMBL3925202 | 0.82 | MAPT (0.47) | MAPTL3MBTL1HPGDMAPK1REN | |
| SCHEMBL78168 | 0.81 | L3MBTL1 (0.46) | MAPTL3MBTL1HPGDMAPK1REN | |
| SCHEMBL2547093 | 0.81 | REN (0.52) | MAPTL3MBTL1HPGDMAPK1REN | |
| SCHEMBL2543486 | 0.81 | REN (0.49) | MAPTL3MBTL1HPGDMAPK1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008088690-A2 | A PROCESS FOR PREPARING DIAZABICYCLO[3.3.1] NONANE COMPOUNDS | MERCK & CO., INC. (US) | 2008-07-24 | — | — | WO | disclosed |