Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 7/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602449 | 0.85 | MAPT (0.51) | L3MBTL1MAPTHPGDMAPK1REN | |
| SCHEMBL78180 | 0.84 | KDM4E (0.46) | L3MBTL1MAPTKDM4EHRH3LMNA | |
| SCHEMBL3925202 | 0.83 | MAPT (0.47) | L3MBTL1MAPTHPGDMAPK1KDM4E | |
| SCHEMBL1751411 | 0.82 | MAPT (0.49) | L3MBTL1MAPTHPGDMAPK1KDM4E | |
| SCHEMBL8407208 | 0.82 | HRH3 (0.43) | L3MBTL1KDM4EHRH3LMNAPOLB | |
| SCHEMBL12601506 | 0.81 | REN (0.48) | L3MBTL1MAPTHPGDMAPK1KDM4E | |
| SCHEMBL8165437 | 0.81 | MAPT (0.48) | L3MBTL1MAPTHPGDMAPK1KDM4E | |
| SCHEMBL5795265 | 0.80 | MAPT (0.58) | L3MBTL1MAPTHPGDMAPK1KDM4E | |
| SCHEMBL78925 | 0.80 | L3MBTL1 (0.45) | L3MBTL1MAPTHPGDMAPK1KDM4E | |
| SCHEMBL5282382 | 0.79 | TSHR (0.62) | L3MBTL1MAPTKDM4EHRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |