Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154002 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL14906997 | 0.75 | LMNA (0.31) | — | |
| SCHEMBL418737 | 0.72 | AR (0.39) | — | |
| SCHEMBL8161475 | 0.70 | KMT2A (0.36) | — | |
| SCHEMBL8639218 | 0.68 | ALDH1A1 (0.47) | — | |
| SCHEMBL8153670 | 0.67 | — | — | |
| SCHEMBL13166694 | 0.66 | AR (0.43) | — | |
| SCHEMBL7765313 | 0.65 | LMNA (0.36) | — | |
| SCHEMBL25468168 | 0.64 | TSHR (0.31) | TSHR | |
| SCHEMBL4410060 | 0.64 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807267-B1 | CROSSLINKED POLYMERS CONTAINING URETHANE GROUPS | NOVARTIS AG (CH) | 2000-03-01 | — | — | EP | disclosed |
| US-5807927-A | POLYVINYL ACETALS MODIFIED BY ISOCYANATO ACRYLATES; CONTACT LENSES | CIBA VISION CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0807267-A1 | CROSSLINKED POLYMERS CONTAINING URETHANE GROUPS | Novartis AG (CH) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996024073-A1 | CROSSLINKED POLYMERS CONTAINING URETHANE GROUPS | NOVARTIS AG (CH) | 1996-08-08 | — | — | WO | disclosed |