SCHEMBL14906997

SCHEMBL14906997

CN1C(=O)N(CO)C(C)(C)C1=O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
RAB9A P51151 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27867344 0.81 KDM4E (0.31) LMNA
SCHEMBL418737 0.80 AR (0.39) LMNARAB9APOLB
SCHEMBL28031486 0.77 RAB9A (0.39) RAB9APOLB
SCHEMBL17372971 0.77
SCHEMBL8154002 0.76 ALDH1A1 (0.40)
SCHEMBL10703017 0.75 RAB9A (0.32) RAB9A
SCHEMBL7217086 0.75 GAA (0.38) RAB9APOLB
SCHEMBL15458745 0.75 AR (0.31)
SCHEMBL12189954 0.75 RAB9A (0.41) LMNARAB9APOLB
SCHEMBL8166140 0.75 TSHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778577-B2 Colored composition, colored cured film, color filter, method for producing color filter, liquid crystal display device, solid-state imaging device, and novel dipyrromethene metal complex compound or tautomer thereof FUJIFILM CORPORATION (JP) 2014-07-15 US disclosed
US-20140038092-A1 COLORED COMPOSITION, COLORED CURED FILM, COLOR FILTER, METHOD FOR PRODUCING COLOR FILTER, LIQUID CRYSTAL DISPLAY DEVICE, SOLID-STATE IMAGING DEVICE, AND NOVEL DIPYRROMETHENE METAL COMPLEX COMPOUND OR TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2014-02-06 US disclosed
US-20130109731-A1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR MAKING SAME BIOMED PROTECT, LLC (US) 2013-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130109731-A1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR MAKING SAME MDH1, MDH2, CHCHD6 LMNA 2309/4885RAB9A 3554/4885POLB 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.